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Showing 1 to 12 of 383 entries
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Biochemical and Parasitological Studies on the Effect of hUCB-Selected CD34(+) Progenitor/Stem Cells in Mice Infected with Schistosoma mansoni.

International journal of stem cells

Abou-Zied AM, Soliman RH, Hefila SM, Imam SA.
PMID: 25473447
Int J Stem Cells. 2014 Nov;7(2):98-107. doi: 10.15283/ijsc.2014.7.2.98.

BACKGROUND AND OBJECTIVES: Placenta and blood that remained in the umbilical cord is routinely available as a discarded tissue after deliveries and it is free of any legal, moral, ethical or religious objections, providing a high number of multipotent...

Growth Properties and Pluripotency Marker Expression of Spontaneously Formed Three-dimensional Aggregates of Human Adipose-derived Stem Cells.

International journal of stem cells

Bogdanova-Jatniece A, Berzins U, Kozlovska T.
PMID: 25473452
Int J Stem Cells. 2014 Nov;7(2):143-52. doi: 10.15283/ijsc.2014.7.2.143.

BACKGROUND AND OBJECTIVES: Recent findings suggest that therapeutic potential of mesenchymal stem cells (MSCs) could be increased through aggregation into three-dimensional (3D) bodies, and different culture methods have been employed to obtain 3D spheroids of MSCs. In the current...

SoxD Transcription Factors: Multifaceted Players of Neural Development.

International journal of stem cells

Ji EH, Kim J.
PMID: 27426080
Int J Stem Cells. 2016 May 30;9(1):3-8. doi: 10.15283/ijsc.2016.9.1.3.

SoxD transcription factor subfamily includes three members, Sox5, Sox6, and Sox13. Like other Sox genes, they contain the High-Mobility-Group (HMG) box as the DNA binding domain but in addition feature the subgroup-specific leucine zipper motif. SoxD genes are expressed...

Genetically Engineered In Vitro Erythropoiesis.

International journal of stem cells

Geiler C, Andrade I, Clayton A, Greenwald D.
PMID: 27426086
Int J Stem Cells. 2016 May 30;9(1):53-9. doi: 10.15283/ijsc.2016.9.1.53.

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the US blood supply for transfusion treatments. Engineered blood produced from hematopoietic stem cell (HSC) derived red blood cells in a laboratory is possible, but...

Umbilical Cord Derived Mesenchymal Stem Cells Useful in Insulin Production - Another Opportunity in Cell Therapy.

International journal of stem cells

Sarang S, Viswanathan C.
PMID: 27426087
Int J Stem Cells. 2016 May 30;9(1):60-9. doi: 10.15283/ijsc.2016.9.1.60.

BACKGROUND AND OBJECTIVES: Type 1 Diabetes Mellitus (T1DM) is an autoimmune disorder resulting out of T cell mediated destruction of pancreatic beta cells. Immunomodulatory properties of mesenchymal stem cells may help to regenerate beta cells and/or prevent further destruction...

Study of the Effect of Route of Administration of Mesenchymal Stem Cells on Cisplatin-Induced Acute Kidney Injury in Sprague Dawley Rats.

International journal of stem cells

Moustafa FE, Sobh MA, Abouelkheir M, Khater Y, Mahmoud K, Saad MA, Sobh MA.
PMID: 27426089
Int J Stem Cells. 2016 May 30;9(1):79-89. doi: 10.15283/ijsc.2016.9.1.79.

BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) have been shown to ameliorate cisplatin-induced acute kidney injury (AKI). The present study compares the efficacy of different routes of MSCs administration on kidney damage and regeneration after cisplatin-induced AKI.METHODS: A single...

Therapeutic Potential of Bone Marrow-Derived Mesenchymal Stem Cells on Experimental Liver Injury Induced by Schistosoma mansoni: A Histological Study.

International journal of stem cells

Fikry H, Gawad SA, Baher W.
PMID: 27426091
Int J Stem Cells. 2016 May 30;9(1):96-106. doi: 10.15283/ijsc.2016.9.1.96.

BACKGROUND AND OBJECTIVES: Bone marrow derived mesenchymal stem cells (BM-MSCs) have been proposed as effective treatment of many diseases owing to their unique ability to differentiate into other cell types in vivo. Schistosoma mansoni (S. mansoni) infection is characterized...

Severe Type 2 Diabetes Induces Reversible Modifications of Endothelial Progenitor Cells Which are Ameliorate by Glycemic Control.

International journal of stem cells

De Pascale MR, Bruzzese G, Crimi E, Grimaldi V, Liguori A, Brongo S, Barbieri M, Picascia A, Schiano C, Sommese L, Ferrara N, Paolisso G, Napoli C.
PMID: 27426095
Int J Stem Cells. 2016 May 30;9(1):137-44. doi: 10.15283/ijsc.2016.9.1.137.

BACKGROUND: Circulating endothelial progenitors cells (EPCs) play a critical role in neovascularization and endothelial repair. There is a growing evidence that hyperglycemia related to Diabetes Mellitus (DM) decreases EPC number and function so promoting vascular complications.AIM OF THE STUDY:...

Moderate Hypoxia Exhibits Increased Endothelial Progenitor Vessel-forming Ability However Gestational Diabetes Caused to Impede Compensatory Defense Reaction.

International journal of stem cells

Dincer UD.
PMID: 27426097
Int J Stem Cells. 2016 May 30;9(1):152-62. doi: 10.15283/ijsc.2016.9.1.152.

Endothelium represents a defense barrier and responds and integrates neuro humoral stimulus which describes as a compensatory mechanism. Endothelium formed with endothelial cells (ECs) and their progenitors. Endothelial progenitor cells (EPCs) represent minor subpopulation of mononuclear cells in the...

Science and ethics: bridge to the future for regenerative medicine.

International journal of stem cells

Patricio VJ.
PMID: 24298338
Int J Stem Cells. 2011 Nov;4(2):79-84. doi: 10.15283/ijsc.2011.4.2.79.

The objective of this article is to reflect on the relationship between regenerative medicine and ethics, using as references the Aristotelian concept of what is ethical and that of Raessler Van Potter about bioethics. To do this, I will...

Dopamine neuron generation from human embryonic stem cells.

International journal of stem cells

Kim YS, Park CH.
PMID: 24298339
Int J Stem Cells. 2011 Nov;4(2):85-7. doi: 10.15283/ijsc.2011.4.2.85.

The capacity of pluripotency and self-renewal of human embryonic stem (hES) cells may provide unlimited cell source for cell replacement therapy. In this manuscript we summarize hES differentiation protocols coculture with PA6 or MS5 stromal cells. After 7∼ 9...

The Porcine Aortic Tissue Culture System in vitro for Stem Cell Research.

International journal of stem cells

Kim DE, Oh KH, Yang JH, Kwon SK, Cho TJ, Lee SB, Nam H, Lee DS, Lee JR, Lee G, Cho J.
PMID: 24298344
Int J Stem Cells. 2011 Nov;4(2):116-22. doi: 10.15283/ijsc.2011.4.2.116.

BACKGROUND AND OBJECTIVES: Due to the shortage of human donors for transplantation, the use of animal organs for xenotransplantation has come into great interest. Xeno-derived vessels and cardiac valves would be possible alternatives for the patient suffering from cardiovascular...

Showing 1 to 12 of 383 entries